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Will Using Latisse Cause my Entire Eyelid to Darken?
Quick Answer: Eyelid discoloration from Latisse can occur where the product has come into repeated contact with the skin. We have many patients that use Latisse and we discuss this possible side effect prior to beginning its use with all patients. If skin discoloration does occur when using Latisse it is typically temporary and is expected to go away once the product is no longer used. Generally speaking it takes about two months for the changes to be reversed.
Clinical Context
Latisse can cause two different pigment changes. Skin darkening along the lash line comes from repeated contact with the product and fades once you stop using it, usually within a couple of months. Separately, prostaglandin eye drops in this class can permanently darken the iris (eye color) in some patients—this is a different, unrelated effect on eye tissue, not skin. If you notice any change in eye color, mention it to your doctor promptly, since that effect does not reverse.
